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Abbott Laboratories' Synthroid (Levothyroxine Sodium Tablets, USP) Confirmed Safe and Effective Through FDA approval, Doctor's Guide:"Abbott Laboratories announced it received U.S. Food and Drug Administration (FDA) approval of its synthetic thyroid hormone replacement therapy, Synthroid® (levothyroxine sodium tablets, USP), for thyroid disease management, as replacement or supplemental therapy for hypothyroidism (underactive thyroid) and pituitary thyroid stimulating hormone suppression. Millions of patients and their physicians have relied on Synthroid for decades to maintain their thyroid health. Formal approval by FDA of Synthroid validates its safety and efficacy. With FDA approval, Abbott is now free to meet full market demand."
http://www.pslgroup.com/dg/21989e.htm

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Doctors' Answers to "Frequently Asked Questions" - Synthroid, Drug InfoNet, Inc.:"Taking thyroid replacement has little to do with weight gain or loss. I know this is counterintuitive, but it is medically the way it is. If taking excessive thyroid would allow weight loss, we wouldn't need drugs like phen-fen, etc. Mohammed Ali tried this in training camp in the 70s and only got tired for his effort. It is true that if your thyroid is over/under active it will affect your weight, but it's not true that replacement medications will have this effect. Weight gain/loss while taking synthroid is no different from someone who is not taking the medication."
Drug InfoNet, Inc.
5760 Commons Park Drive East Syracuse, NY 13057
Telephone: (315) 671-0801 Fax: (201) 313-3377
http://www.druginfonet.com/index.php?pageID=faq/faqsynth.htm

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Levothyroxine, Who is this for? Drugdigest.org:"Levothyroxine, a thyroid hormone, is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. Without this hormone, the body cannot function properly, resulting in poor growth, slow speech, lack of energy, weight gain, hair loss, dry thick skin, and increased sensitivity to cold. When taken correctly, levothyroxine reverses these symptoms. Levothyroxine also is used to treat congenital hypothyroidism (cretinism) and goiter (enlarged thyroid gland). This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information."
http://www.drugdigest.org/DD/DVH/Uses/0,3915,385|Levothyroxine,00.html

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Levoxyl Homepage:"Levoxyl® is what the best dressed thyroids will now be wearing. FDA approved as safe and effective for the treatment of hypothyroidism Proven stabilized formulation† Formulated to release at 100% of label claim Stabilized to ensure that the strength you prescribe is the strength patients receive Levoxyl can help you safely and effectively treat your patients at the dose you prescribe."
Toll Free: 1-866-LEVOXYL (538-6995)
http://www.levoxyl.com/

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levothyroxine sodium - Thyroid: health and medical information about Thyroid Disease, Hypothyroidism, Hyperthyroidism and Thyroid Disease, Medicinenet.com:"Levothyroxine is a synthetic (man-made) version of the principal thyroid hormone, thyroxine (T4), that is made and released by the thyroid gland. Thyroid hormone increases the metabolic rate of cells of all tissues in the body. In the fetus and newborn, thyroid hormone is important for the growth and development of all tissues including bones and the brain. In adults, thyroid hormone helps to maintain brain function, food metabolism, and body temperature, among other effects."
MedicineNet, Inc.
903 Calle Amanecer, Suite 300 San Clemente, CA 92673
Telephone: 949.940.6500 Fax: 949.940.1094, smartservice@medicinenet.com
http://www.medicinenet.com/levothyroxine_sodium/article.htm

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Synthroid Homepage:"Welcome to your online source of information about SYNTHROID. Whether you are seeking information about thyroid disease, or are one of the millions of patients who take SYNTHROID every day, this Web site was designed to provide you with information about thyroid conditions, and information about SYNTHROID. Learn how thyroid disease affects the entire body, the importance of routine testing and about treatment options."
(800) 255-5162
http://synthroid.com/

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Levothyroxine Sodium, RXlist.com: The synthesis and secretion of the major thyroid hormones L-thyroxine (T4) and L-triiodothyronine (T3) from the normally functioning thyroid gland are regulated by complex feedback mechanisms of the hypothalamic-pituitary-thyroid axis
http://www.rxlist.com/cgi/generic/levothy.htm

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Unithroid Homepage:"Levothyroxine sodium is used for the following indications:Hypothyroidism - As replacement or supplemental therapy in congenital or acquired hypothyroidism of any etiology, except transient hypothyroidism during the recovery phase of subacute thyroiditis. Specific indications include: primary (thyroidal), secondary (pituitary), and tertiary (hypothalamic) hypothyroidism and subclinical hypothyroidism. Primary hypothyroidism may result from functional deficiency, primary atrophy, partial or total congenital absence of the thyroid gland, or from the effects of surgery, radiation, or drugs, with or without the presence of goiter. Pituitary TSH Suppression - In the treatment or prevention of various types of euthyroid goiters (see PRECAUTIONS), including thyroid nodules (see PRECAUTIONS), subacute or chronic Iymphocytic thyroiditis (Hashimoto's thyroiditis), multinodular goiter and, as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer."
http://www.unithroid.com/

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Levothyroxine Sodium, Why Prescribed, WholehealthMD.com:"To treat patients with an underactive thyroid gland, goiter (enlarged thyroid gland), and benign and malignant (noncancerous and cancerous) thyroid nodules."
WholeHealthMD LLC
11150 Sunset Hills Road Suite 210
Reston, VA 20190
http://www.wholehealthmd.com/refshelf/drugs_view/1,1524,364,00.html

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Articles:

Doctors' Answers to "Frequently Asked Questions" - Hypothyroidism:
http://www.druginfonet.com/faq/faqhypot.htm

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Doctors' Answers to "Frequently Asked Questions" - Synthroid:
http://www.druginfonet.com/faq/faqsynth.htm

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Drug Company Agrees To Pay $135 Million To Synthroid Users:
http://www.dailybruin.ucla.edu/DB/issues/97/08.25/news.lawsuit.html

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History of Thyroid Hormone Replacement:
http://www.the-thyroid-society.org/replacement.html

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Associations:

American Association of Clinical Endocrinologists:
1000 Riverside Ave.; Suite 205, Jacksonville, FL 32204
Voice (904) 353-7878, Fax (904) 353-8185
http://www.aace.com/

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American Thyroid Association: The mission of the American Thyroid Association is to promote scientific and public understanding of the biology of the thyroid gland and the pathogenesis and management of its diseases in order to prevent, diagnose and treat thyroid diseases and thereby improve quality of life.
Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, Fax 718-882-6085, EMAIL: info@thyroid.org,
http://www.thyroid.org/

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The Endocrine Society: The Endocrine Society is the world's largest and most active organization devoted to the research, study and clinical practice of endocrinology.
4350 East West Highway, Suite 500, Bethesda, Maryland 20814-4410, Tel: (301) 941-0200 * Fax: (301) 941-0259, Email: endostaff@endo-society.org
http://www.endo-society.org/

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National Graves' Disease Foundation:
http://www.ngdf.org/

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The Thyroid Society:
http://www.the-thyroid-society.org/replacement.html

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Research:

Human Biological Data Interchange (HBDI): A Resource for Genetic Research - Diabetes, Thyroid Disease and Autism
1880 JFK Blvd., 6th Fl., Philadelphia, PA 19103
Phone (800) 345-4234, Fax (215) 557-7154
http://www.hbdi.org/

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